出生年月：1981.10.25

民族：漢

職稱：副教授

學科專業(yè)：藥物分析,、藥物化學

研究方向：水溶性熒光納米材料的合成及其在藥物分析中的應用研究

電子郵箱：[email protected]

 

學習經歷

1999 -2003  就讀于華中師范大學化學學院,，獲理學學士學位

2004-2009   碩博連讀于武漢大學化學與分子科學學院分析化學專業(yè) 獲得博士學位

2007 -2008  作為交換生及研究助理在香港浸會大學化學系從事研究工作

 

工作經歷

2009年至今任教于中南民族大學現(xiàn)為中南民族大學藥學院教師,，主要從事分析化學,、化學生物學方面的教學和科研工作。

 

承擔的重要項目：

[1]    水溶性手性量子點的制備及雙色熒光法手性藥物檢測研究,、國家自然科學基金青年項目,、國家自然科學基金委，2012-2014年,，主持

[2]    基于量子點熒光可逆變化模式的鉑類抗癌藥物檢測研究,、湖北省自然科學基金青年項目、湖北省科技廳,，2011-2013年,，主持

[3]    基于量子點熒光“turn off-on”可逆模式的G-四鏈體與靶向抗癌藥物作用研究、湖北省自然科學基金面上項目,、湖北省科技廳,，2016 -2017年,，主持

 

近期發(fā)表的部分論文目錄：

[1] Dan Zhao*, Changpeng Zhang, Huan Liu, Yan Jiao, Xincai Xiao. Gadolinium-doped carbon dots with dual enzyme activity for visual detection of Cu²⁺ and antibacterial applications, ACS Applied Nano Materials, 2024, 7 (4), 4228-4238.

[2] Dan Zhao*, Huan Liu, Mengyu Xu, Chengxin Yin, Xincai Xiao, Kang Dai*. Functional carbon dots-hydrogel complex for selective antibacterial and detection applications. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 314: 124195.

[3] Huan Liu, Dan Zhao*, Changpeng Zhang, Minghao Li, Shijie Zhang, Xincai Xiao, One-step preparation of MnO₂ nanozyme by PS-CDs for antibacterial, inhibition of S. aureus biofilm growth and colorimetric assay of tiopronin, Journal of Industrial and Engineering Chemistry, 2023, 125, 127-135.

[4] Dan Zhao*, Xiaoyun Li, Mengyu Xu, Yan Jiao, Huan Liu, Xincai Xiao, Haiyan Zhao, Preparations of antibacterial yellow-green-fluorescent carbon dots and carbon dots-lysozyme complex and their applications in bacterial imaging and bacteria/biofilm inhibition/clearance, International Journal of Biological Macromolecules, 2023, 231, 123303.

[5] Dan Zhao*, Mengyu Xu, Kang Dai, Huan Liu, Yan Jiao, Xincai Xiao, The preparation of chiral carbon dots and the study on their antibacterial abilities, Materials Chemistry and Physics, 2023, 295, 127144.

[6] Meng Liu?, Dan Zhao?, Hui Lv, Yunjing Liang, Yannan Yang, Zongguo Hong, Jingxue Liu, Kang Dai*, Xincai Xiao*, Controllable fabrication and oil–water separation properties of polyethylene terephthaloyl-ethylenediamine-IPN-poly(N-Isopropylacrylamide) microcapsules, Polymers, 2023, 15, 53.

[7] Dan Zhao*, Rui Zhang, Mengyu Xu, Xiaoyun Li, Yan Jiao, Xincai Xiao, A novel quaternized carbon dot–papain complex for the double-target anti-biofilm activity and visualization-ratio fluorescence dual-mode detection of H₂O₂, Materials Chemistry Frontiers, 2022, 6(19), 2848-2858.

[8] Dan Zhao*, Rui Zhang, Xuemei Liu, Xiaoyun Li, Mengyu Xu, Xianju Huang, Xincai Xiao, Screening of chitosan derivatives-carbon dots based on antibacterial activity and application in anti-Staphylococcus aureus biofilm, International Journal of Nanomedicine, 2022, 17, 937-952.

[9] Dan Zhao*, Huan Liu, Zhixia Zhang, Xincai Xiao, Jun Li, Preparation of green luminescent silicon quantum dots by synergistic method for VB₁₂ detection and antimicrobial property research application, Colloids and Surfaces B: Biointerfaces, 2022, 220, 112868.

[10] Dan Zhao*, Zhixia Zhang, Xuemei Liu, Rui Zhang, Xincai Xiao, Rapid and low-temperature synthesis of N, P co-doped yellow emitting carbon dots and their applications as antibacterial agent and detection probe to sudan red I, Materials Science and Engineering C: Materials for Biological Applications, 2021, 119, 111468.

[11] Dan Zhao*, Xuemei Liu, Rui Zhang, Xincai Xiao, Jun Li, Preparation of two types of silver-doped fluorescent carbon dots and determination of their antibacterial properties, Journal of Inorganic Biochemistry, 2021, 214, 111306.

[12] Dan Zhao*, Xuemei Liu, Rui Zhang, Xianju Huang, Xincai Xiao, Facile one-pot synthesis of multifunctional protamine sulfate-derived carbon dots for antibacterial applications and fluorescence imaging of bacteria, New Journal of Chemistry, 2021, 45(2), 1010-1019.

[13] Dan Zhao*, Rui Zhang, Xuemei Liu, Xianju Huang, Xincai Xiao, LinYuan, One-step synthesis of blue–green luminescent carbon dots by a low-temperature rapid method and their high-performance antibacterial effect and bacterial imaging, Nanotechnology, 2021, 32(15), 155101.

[14] Dan Zhao*, Rui Zhang, Mengyu Xu, Xincai Xiao, Haiyan Zhao, Xianju Huang, Multifunctional biomedical applications of nitrogen and sulfur co-doped carbon dots, Journal of Biomedical Nanotechnology, 2021, 17, 1598-1611.

[15] Dan Zhao*, Zhixia Zhang, CaiMao Li, Xincai Xiao, Jun Li, Xuemei Liu, Han Cheng, Yellow-emitting hydrophobic carbon dots via solid-phase synthesis and their applications, ACS Omega, 2020, 5(35), 22587-22595.

[16] Dan Zhao*, Xuemei Liu, Chunjin Wei, Yimo Qu, Xincai Xiao, Han Cheng, One-step synthesis of red-emitting carbon dots via a solvothermal method and its application in the detection of methylene blue, RSC Advances, 2019, 9(51), 29533-29540.

[17] Dan Zhao*, Xuemei Liu, Zhixia Zhang, Rui Zhang, Liangxiu Liao, Xincai Xiao, Han Cheng, Synthesis of multicolor carbon dots based on solvent control and its application in the detection of crystal violet, Nanomaterials, 2019, 9(11), 1556.

[18] Jun Li, Shiyao Ma, Xincai Xiao, Dan Zhao*, The one-step preparation of green-emissioned carbon dots through hydrothermal route and its application, Journal of Nanomaterials, 2019, 2019, 8628354.

[19] Zhixia Zhang, Chunjin Wei, Wenting Ma, Jun Li, Xincai Xiao, Dan Zhao*, One-step hydrothermal synthesis of yellow and green emitting silicon quantum dots with synergistic effect, Nanomaterials, 2019, 9(3), 466.

[20] Zhixia Zhang, Dan Zhao*, Yonghao Pang, Jian Hao, Xincai Xiao, Yan Hu, Application of silicon quantum dots in the detection of formaldehyde in water and organic phases, Current Analytical Chemistry, 2019, 15(5), 560-566.

[21] Dan Zhao, Wenting Ma, Rong Wang, Xinzhou Yang, Jun Li, Ting Qiu, Xincai Xiao*, The preparation of green fluorescence-emissioned carbon dots/poly (N-isopropylacrylamide) temperature-sensitive hydrogels and research on their properties, Polymers, 2019, 11(7), 1171.

[22] Shiyao Ma, Tong Yue, Xincai Xiao, Han Cheng, Dan Zhao*, A proof of concept study of preparing ultra bright silicon quantum dots based on synergistic effect of reductants, Journal of Luminescence, 2018, 201, 77-84.

[23] Dan Zhao, Wenting Ma, Caixin Xiao*, The recognition of sweat latent fingerprints with green-emitting carbon dots, Nanomaterials, 2018, 8, 612-621.

[24] Chunjin Wei, Jun Li, Xincai Xiao, Tong Yue, Dan Zhao*, The one-step preparation of green-emission carbon dots based on the deactivator-reducing reagent synergistic effect and the study on their luminescence mechanism, RSC Advances, 2018, 8, 20016-20024.

[25] Fang Gao, Shiyao Ma, Jun Li, Kang Dai, Xincai Xiao, Dan Zhao*, Weifan Gong, Rational design of high quality citric acid-derived carbon dots by selecting efficient chemical structure motifs, Carbon, 2017, 112, 131-141.

[26] Fang Gao, Shiyao Ma, Xincai Xiao, Yan Hu, Dan Zhao*, Zhike He*, Sensing tyrosine enantiomers by using chiral CdSe/CdS quantum dots capped with N-acetyl-L-cysteine, Talanta, 2017, 163, 102-110.

[27] Xiaoling Xu, Fang Gao, Xincai Xiao, Yan Hu, Chaozhen Zhu, Dan Zhao*, Selective recognition of cis-trans-isomers of platinum drugs and the detection of triplex DNA based on fluorescence reversible model of quantum dots, Journal of Pharmaceutical and Biomedical Analysis, 2017, 134, 94-99.

[28] Xiaoling Xu, Shiyao Ma, Xincai Xiao, Yan Hu, Dan Zhao*, The preparation of high-quality water-soluble silicon quantum dots and their application in the detection of formaldehyde, RSC Advances, 2016, 6, 98899-98907.

[29] Dan Zhao?, Yao Fan?, Fang Gao, Tianming Yang*, “Turn-off-on” fluorescent sensor for (N-methyl-4-pyridyl) porphyrin-DNA and G-quadruplex interactions based on ZnCdSe quantum dots, Analytica Chimica Acta, 2015, 888, 131-137.

[30] Fang Gao, Jiaotian Li, Fengxue Wang, Tanming Yang, Dan Zhao*, Synthesis and characterization of high-quality water-soluble CdMnTe quantum dots capped by N-acetyl-L-cysteine through hydrothermal method, Journal of Luminescence, 2015, 159, 32-37.

[31] Chunjin Wei, Jinyu Li, Fang Gao, Shuxia Guo, Yongcui Zhou, Dan Zhao*, One-step synthesis of high-quality water-soluble CdSe quantum dots capped by N-acetyl-L-cysteine via hydrothermal method and their characterization, Journal of Spectroscopy, 2015, 369145.

[32] Dan Zhao, Jiaotian Li, Tianming Yang, Zhike He*, “Turn off-on” fluorescent sensor for platinum drugs-DNA interactions based on quantum dots, Biosensors and Bioelectronics, 2014, 52, 29-35.

[33] Dan Zhao, Jiaotian Li, Fang Gao, Cuiling Zhang, Zhike He*, Facile synthesis and chara- cterization of highly luminescent UV-blue-emitting ZnSe/ZnS quantum dots via a one-step hydrothermal method, RSC Advances, 2014, 4, 47005-47011.

[34] Fang Gao, Yuying Liu, Yao Fan, Dan Zhao*, Synthesis of N-acetyl-L-cysteine -capped ZnCdSe quantum dots via hydrothermal method and their characterization, Science and Technology of Advanced Materials, 2014, 15, 055001.

[35] Jiaotian Li, Tianming Yang, W. H. Chan, Martin M. F. Choi, Dan Zhao*; Synthesis of high-quality N?acetyl?L?cysteine-capped CdTe quantum dots by hydrothermal route and the characterization through MALDI-TOF mass spectrometry, Journal of Physical Chemistry C, 2013, 117, 19175-19181.

[36] Tianming Yang, Qingyi He, Yuying Liu, Chaozhen Zhu, Dan Zhao*, Water-soluble N-acetyl-L-cysteine-capped CdTe quantum dots application for Hg(II) detection, Journal of Analytical Methods in Chemistry, 2013, 902951.

[37] Dan Zhao, Yang Fang, Haoyuan Wang and Zhike He* Synthesis and characterization of high-quality water-soluble CdTe: Zn2+ quantum dots capped by N-acetyl-L-cysteine via hydrothermal method,，J. Mater. Chem., 2011, 21, 13365-13370.

[38] Jiaotian Li, Tianming Yang, W. H. Chan, Martin M. F. Choi, and Dan Zhao*, Synthesis of High-Quality N?Acetyl?L?Cysteine-Capped CdTe Quantum Dots by Hydrothermal Route and the Characterization through MALDI-TOF Mass Spectrometry, J. Phys. Chem. C 2013, 117, 19175?19181

[39] Dan Zhao, Zhike He, Pui Shan Chan, Ricky N. S. Wong, Nai Ki Mak,*, Albert W. M. Lee, and Wing Hong Chan*, NAC-Capped Quantum Dot as Nuclear Staining Agent for Living Cells via an In ViWo Steering Strategy, J. Phys. Chem. C 2010, 114, 6216–6221.

[40] Dan Zhao, WingHong Chan*, Zhike He*, Ting Qiu. Quantum dot-ruthenium complex dyads: recognition of double-Strand DNA through dual-color fluorescence detection, Analytical Chemistry 2009, 81, 3537-3543.

[41] Dan Zhao, Zhike He, WingHong Chan*, Martin M. F. Choi*. Synthesis and characterization of high-quality water-soluble near-infrared- emitting CdTe/CdS quantum dots capped by N-acetyl-L-cysteine via hydrothermal method, Journal of Physical Chemistry C 2009, 113, 1293.

[42] Dan Zhao, Juan Du, Yanguo Chen, Xinghu Ji, Zhike He*, WingHong Chan. A quencher-tether-ligand probe and its application in biosensor based on conjugated polymer, Macromolecules 2008, 41, 5373.

[43] Yanguo Chen, Dan Zhao, Zhike He*, Xinping Ai. Fluorescence quenching of water-soluble conjugated polymer by metal cations and its application in sensor, Spectrochimica Acta Part A 2007, 66, 448.