基本信息

姓名：王文靜

出生年月：1990年1月

民族：漢族

職稱：講師

學(xué)科方向：藥物化學(xué)

研究方向：天然藥物化學(xué)

郵箱：[email protected]

教育及工作經(jīng)歷

2020.10—至今 中南民族大學(xué)藥學(xué)院，講師

2018.6—2020.5 華中科技大學(xué)基礎(chǔ)醫(yī)學(xué)院,，博士后（合作導(dǎo)師：張勇慧教授,、王小川教授）

2015.9—2018.9 華中科技大學(xué)藥學(xué)院，醫(yī)學(xué)博士（導(dǎo)師：張勇慧教授）

2012.9—2015.6 沈陽藥科大學(xué),，理學(xué)碩士

2008.9—2012.6 湖北中醫(yī)藥大學(xué),，理學(xué)學(xué)士

教學(xué)工作

累計(jì)承擔(dān)多門本科生和研究生課程教學(xué)工作，主要包括《結(jié)構(gòu)生物學(xué)》,、《藥學(xué)儀器分析》,、《高等中藥化學(xué)》、《中藥化學(xué)前沿》等,；發(fā)表核心教研論文1篇,，參編學(xué)術(shù)專著1部。指導(dǎo)國家級“大學(xué)生創(chuàng)新訓(xùn)練計(jì)劃”1項(xiàng),，并獲“優(yōu)秀項(xiàng)目獎”,；指導(dǎo)研究生團(tuán)隊(duì)獲“建行杯”省級銅獎1項(xiàng)，“互聯(lián)網(wǎng)+”校級獎2項(xiàng)

主要榮譽(yù)和獲獎

2024年，中南民族大學(xué)“優(yōu)秀班導(dǎo)師”

2022年,，中南民族大學(xué)“第六屆科普講解大賽”三等獎

并多次獲評中南民族大學(xué)“創(chuàng)新指導(dǎo)優(yōu)秀教師”,、“挑戰(zhàn)杯”大學(xué)生課外學(xué)術(shù)科技作品競賽“優(yōu)秀指導(dǎo)老師”

科研項(xiàng)目
1. 內(nèi)生真菌Aspergillus aculeatus中新穎結(jié)構(gòu)抗耐藥細(xì)菌活性色原酮二聚體的定向挖掘及其作用機(jī)制解析，國家自然科學(xué)基金面上項(xiàng)目,，2024.1-2027.12,，49萬元。

2. 石蒜內(nèi)生菌簡青霉次生代謝產(chǎn)物及其生物活性研究,，國家自然科學(xué)基金青年項(xiàng)目,，2020.01-2022.12，24萬元,。

3. 簡青霉次生代謝產(chǎn)物及其生物活性研究,，中國博士后科學(xué)基金面上項(xiàng)目，2019.1-2020.12,，8萬元,。

4. 分子網(wǎng)絡(luò)驅(qū)動的Penicillium屬真菌中新型抗三陰乳腺癌活性分子定向挖掘及其作用機(jī)制研究，武漢市自然科學(xué)基金探索計(jì)劃（晨光計(jì)劃）,，2024.6-2026.6,，10萬元。

5. 細(xì)果角茴香內(nèi)生真菌Aspergillus versicolor化學(xué)成分及其生物活性研究,，中南民族大學(xué)中央高?；究蒲袠I(yè)務(wù)費(fèi)項(xiàng)目，2022.3-2024.3,，5萬元,。

代表性研究成果

截至目前，已在Organic Letters,、Journal of Natural Products,、Phytochemistry等本領(lǐng)域權(quán)威期刊上發(fā)表SCI論文30余篇

(1) Shuzhi Liu^#, Wenjing Wang^#, Qingpei Liu, Ming Yao, Liangxiu Liao, Shuaibiao Gao, Yi Yu; Xiaolong Yang^(*), Emerindanols A and B: Two bipolyhydroindenol sesterterpenes with 5/6–6/5 coupled ring system discovered by genome mining, Organic Letters, 2024, 26, 4475.

(2) Wenjing Wang, Junguo Huang, Liangxiu Liao, Xiaolong Yang, Chunmei Chen, Junjun Liu, Hucheng Zhu^(*), Yonghui Zhang^(*), Chae-type cytochalasans from coculture of Aspergillus flavipes and Chaetomium globosum, Phytochemistry, 2024, 219, 113961.

(3) Sulu Qin, Jiaxin Ding, Chengyun Huang, Jing Li, Ming Yao, Qingpei Liu, Wenjing Wang^(*), Xiaolong Yang^(*), Secondary metabolites from Pseudallescheria boydii and their anti-melanoma activity, Tetrahedron, 2023, 147, 133663.

(4) Liangxiu Liao, Junguo Huang, Qingpei Liu, Ming Yao, Wenjing Wang^(*), Xiaolong Yang^(*), Two new quinazoline alkaloids produced by Aspergillus versicolor and their antimicrobial activities, Journal of Asian Natural Products Research, 2023, 26, 320.

(5) Wenjing Wang^#, Liangxiu Liao^#, Zediao Huang, Futing Wei, and Xiaolong Yang^(*), Thiazolo[5,4?b]pyridine alkaloid and seven ar-bisabol sesquiterpenes produced by the endophytic fungus Penicillium janthinellum, ACS Omega, 2022, 7, 35280–35287.

(6) Liangxiu Liao, Zediao Huang, Futing Wei, Wenjing Wang^(*), Xiaolong Yang^(*), New chromone analog and pyrrole alkaloid produced by Penicillium sclerotiorum and their antibacterial activity, Journal of Asian Natural Products Research, 2022, 25, 225.

(7) Qinglin Mou, Shengxiang Yang, Ting Xiang, Wenwen Liu, Jian Yang, Lanpin Guo^(*), Wenjing Wang^(*), Xiaolong Yang^(*), New cytochalasan alkaloids and cyclobutane dimer from an endophytic fungus Cytospora chrysosperma in Hippophae rhamnoides and their antimicrobial activities, Tetrahedron Letters, 2021, 87, 153207.

(8) Wenjing Wang, Chong Dai, Jianping Wang, Hucheng Zhu, Chunmei Chen^(*), Yonghui Zhang^(*), Polysubstituted Phenyl Glucosides Produced by the Fungus Metarrhizium anisopliae, Current Medical Science, 2020, 40, 232–238.

(9) Wenjing Wang, Fanrong Zeng, Qiong Bie, Chong Dai,Chunmei Chen, Qingyi Tong, Junjun Liu, Jianping Wang, Yuan Zhou, Hucheng Zhu^(*), Yonghui Zhang^(*), Cytochathiazines A?C: Three Merocytochalasans with a 2H-1,4-Thiazine Functionality from Coculture of Chaetomium globosum and Aspergillus flavipes, Organic Letters, 2018, 20, 6817-6821.

(10) Wenjing Wang, Jiaojiao Gong, Xiaorui Liu, Chong Dai, Yanyan Wang, Xiaonian Li, Jianping Wang, Zengwei Luo, Yuan Zhou, Yongbo Xue, Hucheng Zhu, Chunmei Chen^(*), Yonghui Zhang^(*), Cytochalasans produced by the co-culture of Aspergillus flavipes and Chaetomium globosum, Journal of Natural Products, 2018, 81, 1578–1587.

(11) Wenjing Wang, Xiao Wan, Junjun Liu, Jianping Wang, Hucheng Zhu, Chunmei Chen^(*), Yonghui Zhang^(*), Two New Terpenoids from Talaromyces purpurogenus, Marine Drugs, 2018,16, 150.

(12) Wenjing Wang, Danyi Li, Yanchun Li, Huiming Hua, Enlong Ma^(*), Zhanlin Li^(*). Caryophyllene Sesquiterpenes from the Marine-Derived Fungus Ascotricha sp. ZJ-M?5 by the One Strain-Many Compounds Strategy. Journal of Natural Products, 2014, 77, 1367–1371.