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李昕陽

發(fā)布時間:2024-03-29 瀏覽次數(shù):

出生年月:1990-01

   族:漢

   稱:副教授

學(xué)科專業(yè):真菌天然產(chǎn)物化學(xué)與合成生物學(xué)

   箱:[email protected]

 

教育經(jīng)歷

2015.09-2019.06:浙江大學(xué),醫(yī)學(xué)博士

2012.09-2015.06:南京中醫(yī)藥大學(xué),醫(yī)學(xué)碩士

2008.09-2012.06:陜西中醫(yī)藥大學(xué),醫(yī)學(xué)學(xué)士

 

工作經(jīng)歷

2023.07至今:中南民族大學(xué)藥學(xué)院,,副教授

2019.09-2022.03,東京大學(xué),,博士后,合作導(dǎo)師:Ikuro Abe教授

 

主要研究方向

1.   真菌天然產(chǎn)物生物合成途徑解析

2.   真菌天然產(chǎn)物生物合成酶學(xué)機(jī)制研究

3.   基于基因組挖掘手段的天然產(chǎn)物發(fā)現(xiàn)及其生物合成研究

 

科研項(xiàng)目

國家自然科學(xué)基金青年基金項(xiàng)目(22307148),2024.01-2026.12,,主持

 

代表性研究成果

1.    Xinyang Li, Jinzhong Xu*, Pinmei Wang, Wanjing Ding. Novel Indole Diketopiperazine Stereoisomers from a Marine-Derived Fungus Aspergillus sp. Mycology. 2023, 14, 1-10.

2.    Xinyang Li?, He-Ping Chen?, Lin Zhou?, Jing Fan, Takayoshi Awakawa, Takahiro Mori, Richiro Ushimaru*, Ikuro Abe*, Ji-Kai Liu*. Cordycicadins A-D, Antifeedant Polyketides from the Entomopathogenic Fungus Cordyceps cicadae JXCH1. Org. Lett. 2022, 24, 8627-8632.

3.    Qing-Yuan Wang?, He-Ping Chen?, Kai-Yue Wu, Xinyang Li*, Ji-Kai Liu*. Antibacterial and β-Site amyloid precursor protein cleaving enzyme 1 inhibitory polyketides from the fungus Aspergillus chevalieri. Front. Microbiol. 2022, 13, 1051281.

4.    Lin Zhou?, He-Ping Chen?, Xinyang Li*, Ji-Kai Liu*. Ganoaustralins A and B, Unusual Aromatic Triterpenes from the Mushroom Ganoderma australe. Pharmaceuticals. 2022, 15, 1520.

5.    Xinyang Li?, Takayoshi Awakawa?, Takahiro Mori, Meiqi Ling, Bin Wu, Ikuro Abe*. Heterodimeric Non-heme Iron Enzymes in Fungal Meroterpenoid Biosynthesis. J. Am. Chem. Soc. 2021, 143, 21425-21432.

6.    Xinyang Li, Jian-ming Lv, Dan Hu, Ikuro Abe*. Biosynthesis of Alkyne-containing Natural Products. RSC Chem. Biol. 2021, 2, 166-180.

7.    Suoyu Cen, Jia Jia, Yichao Ge, Yihan Ma, Xinyang Li, Jihua Wei, Yuefan Bai, Xiaodan Wu, Jianfeng Song, Hongkai Bi, Bin Wu*. A New Antibacterial 3,5-dimethylorsellinic Acid-based Meroterpene from the Marine Fungus Aspergillus sp. CSYZ-1. Fitoterapia, 2021, 152, 104908.

8.    Jinyan Jiang, Xinyang Li, Takahiro Mori, Takayoshi Awakawa*, Ikuro Abe*. Novel Cyclohexyl Meroterpenes Produced by Combinatorial Biosynthesis. Chem. Pharm. Bull., 2021, 69, 444-446.

9.    Xinyang Li, Wanjing Ding, Pinmei Wang, Jinzhong Xu*. Two Novel Aspochalasins from the Gut Fungus Aspergillus sp. Z4. Mar. Drugs, 2018, 16, 343.

10. Xinyang Li, Zhanhai Zhao, Wanjing Ding, Bin Ye, Pinmei Wang, Jinzhong Xu*. Aspochalazine A, a Novel Polycyclic Aspochalasin from the Fungus Aspergillus sp. Z4. Tetrahedron Lett, 2017, 58, 2405-2408.

(?Co-first author; *Corresponding author)

 

作者:   責(zé)編:陳博   審核:   上傳:

地址:中國-湖北-武漢 民族大道182號中南民族大學(xué)藥學(xué)院 郵編:430074
電話:027-67841196  Fax: 027-67841196
? 2016 中南民族大學(xué)藥學(xué)院