出生年月：1989-04

民族：漢

職稱：講師

學科專業(yè)：藥物化學

研究方向：天然藥物化學/真菌化學

電子郵箱：[email protected]

一、教育和工作經(jīng)歷

2023.04-至今：中南民族大學，藥學院,，講師

2021.07-2024.07：中南民族大學，藥學院,，預備師資

2018.09-2021.07：中國科學院昆明植物研究所,，理學博士

2015.09-2018.07：中國科學院昆明植物研究所，理學碩士

2011.09-2015.07：云南農(nóng)業(yè)大學，農(nóng)學學士

二,、研究方向：

1.藥用植物藥效物質(zhì)基礎(chǔ)及生物功能研究

2.真菌天然產(chǎn)物的結(jié)構(gòu)及生物功能研究

三,、主持的科研項目：

(1) 國家自然科學基金青年基金項目, 82204239，2023-01至2025-12,，主持

(2) 湖北省自然科學基金青年基金, 2022CFB920,，2022-12至2024-06，主持

(3) 中央高?；究蒲袠I(yè)務(wù)費專項資金自科青年項目, CZQ23047, 2023-04至2026-04,，主持

四、代表性研究成果

(1) Shi Baobao, Lu Jingsong, Wu Jing, Bao Meifen, Cai, Xianghai , Symmetric cytotoxic trimeric and dimeric indole alkaloids isolated from Bousigonia angustifolia. Organic Chemistry Frontiers, 2021, 8(11): 2601-2607.

(2) Shi Baobao, Kongkiatpaiboon Sumet, Chen Gao, Schinnerl Johann, Cai* Xianghai, Nematocidal alkaloids from the roots of Stemona mairei (H.Lév.)K.Krause and identification of their pharmacophoric moiety. Bioorganic Chemistry, 2023, 130: 106239.

(3) Ai Honglian¹, Shi Baobao¹, Li Wei¹, He Juan, Li Zhenghui, Feng Tao*, Liu Jikai*, Bipolarithizole A, an antifungal phenylthiazole-Sativene merosesquiterpenoid from potato endophytic fungus Bipolaris eleusines. Organic Chemistry Frontiers, 2022, 9(7): 1814-1819.

(4) Shi BaoBao¹, Tian Chun¹, Lv Xiao, Schinnerl Johann, Ye Ke, Guo Hui, Xu Fan, He Yu, Ai, HongLian* ; Liu JiKai*, Boerelasins A-D, Four Unprecedented Cytochalasins from the Endophytic Fungus Boeremia Exigua. Journal of Organic Chemistry, 2023, 88: 13926-13933

(5) Shi Baobao¹, Ai Honglian¹, Duan Kaiting, Feng Tao*, Liu Jikai*, Ophiorrhines F and G, key biogenetic intermediates of ophiorrhine Alkaloids from Ophiorrhiza japonica and their immunosuppressant activities. Journal of Natural Products, 2022, 85(2): 453-457.

(6) Shi BaoBao¹, Xu Fan¹, Zhang GuangRu, He Yu, Liu Qing, Feng MengLin, Li ZhengHui*, Liu JiKai*. Glucoconjugated monoterpene indole alkaloids with xanthine oxidase inhibitory activity from Ophiorrhiza japonica. Phytochemistry, 2024, 224, 114169.

(7) Fan YinZhong, Tian Chun, Tong ShunYao, Liu Qing, Xu Fan, Shi BaoBao*, Ai HongLian*, Liu JiKai*, Chromones from the endophytic fungus Bipolaris eleusines. Phytochemistry, 2024, 221: 114046.

(8) Fan YinZhong, Shi BaoBao*. Endophytic fungi from the four staple crops and their secondary metabolites. International Journal of Molecular Sciences, 2024, 25(11): 6057

(9) Ai Honglian¹, Lv Xiao¹, Ye Ke, Wang Mengxi, Huang Rong, Shi, Baobao*, Li, Zhenghui*. Four new highly oxygenated eremophilane sesquiterpenes from an endophytic fungus Boeremia exigua Isolated from Fritillaria hupehensis. Journal of Fungi, 2022, 8:492.

(10) Shi Baobao, Chen, Jing, Bao, Meifen, Zeng Ying*, Cai, Xianghai*. Alkaloids isolated from Tabernaemontana bufalina display xanthine oxidase inhibitory activity. Phytochemistry, 2019, 166: 112060.

(11) Zhang Xian, Fan Yinzhong, Ye Ke, Pan Xiaoyan, Ma Xujun, Ai Honglian*, Shi Baobao*, Liu Jikai*. Six unprecedented cytochalasin derivatives from the potato endophytic fungus Xylaria curta E10 and their cytotoxicity. Pharmaceuticals, 2023, 16: 193

(12) Shi Baobao¹, Zhang Guangru¹, Li Zhenghui *, Liu Jikai*. Three new oxygenated yohimbane-type alkaloids from Ophiorrhiza japonica. Fitoterapia, 2023, 166: 105442.

(13) Shi Baobao, Wang Fang, Chen Gao, Schinnerl Johann*, Zeng Ying*, Cai*, Xianghai. Dimeric and monomeric dihydrostilbenes from the roots of Stemona mairei together with their hypoglycemic activities. Tetrahedron, 2021, 79: 131783.

(14) Tian Chun, Xu Fan, He Yu, Ai Hong-Lian, Shi BaoBao*, Liu JiKai,* Isolation, absolute configuration and immunosuppressant activities of pyrrole and furanone derivatives from the edible mushroom Grifola frondose. Phytochemistry Letters, 2024, 61, 242-243

(15) Xu Fan¹, Pan Xiaoyan¹, Cai Baixiang, Fan Yinzhong, Shi Baobao*, Liu Jikai*, Currephila A, a new chromanol derivative from the endophytic fungus Curreya pityophila. Records of Natural Products, 2024, 18, 285-289.

五,、近年授權(quán)專利：

（2）石寶寶, 劉吉開, 艾洪蓮, 馮濤, 李正輝,。一種來源于日本蛇根草的新型異胡豆苷類衍生物及其制備方法和應(yīng)用，ZL202210074390.1

（3）劉吉開, 石寶寶, 黃蓉, 王獻, 陳乾, 董智慧, 沈慧慧, 伍興,。一種細葉萼距花精致組分和單體化合物的制備方法及其在化妝品中的應(yīng)用, ZL202310428961.1