姓名:劉新瓊
職務(wù)/職稱:教授
研究方向:植物遺傳學(xué)
通訊地址:中南民族大學(xué)生命科學(xué)學(xué)院3樓B區(qū)305室
聯(lián)系電話:027-67842689
Email:liuxinqiong@mail.scuec.edu.cn
一、學(xué)習(xí)及工作經(jīng)歷
1,、1990.9-1994.7:湖北農(nóng)學(xué)院(現(xiàn)長江大學(xué))植物保護專業(yè),,獲農(nóng)學(xué)學(xué)士學(xué)位
2,、1994.9-1997.6:華中農(nóng)業(yè)大學(xué)植物病理學(xué)專業(yè),,獲農(nóng)學(xué)碩士學(xué)位
3,、2002.9-2005.6:華南農(nóng)業(yè)大學(xué)分子植物病理學(xué)專業(yè),,獲農(nóng)學(xué)博士學(xué)位
4,、1997.7-2002.8:長江蔬菜雜志社任科技編輯
5,、2009.10-2011.10:日本農(nóng)業(yè)生物資源研究所JSPS博士后
6、2005.7-至今:中南民族大學(xué)生命科學(xué)學(xué)院從事教學(xué)和科研工作
二,、科研活動及成果
(一)主要研究方向
1,、聚焦植物誘導(dǎo)抗病基因的挖掘與分子機理研究。
2,、植物源提取液的抑菌篩選及作用機理研究,。
(二)主持的科研項目
1、2022.11-2025.12,, 浙江溫嶺和泰水產(chǎn)有限公司,, HZY22119,甲殼類廢棄物提煉生物活性物質(zhì)的研究及開發(fā),。
2,、2014.01-2017.12,國家自然科學(xué)基金面上項目,,31370306,,水楊酸應(yīng)答新基因 OsAAA-ATPase-1 在水稻廣譜抗病反應(yīng)中的分子機理研究。
3,、2014.01-2016.12,,湖北省自然科學(xué)基金重點項目,2013CFA098,,利用廣譜抗性相關(guān)基因OsAAA-ATPase-1創(chuàng)制水稻抗病性新材料,。
4、2014.01-2016.12,,國家重大項目轉(zhuǎn)基因?qū)m?(子課題),,2014ZX0800904B,稻瘟病廣譜抗性基因的克隆及其應(yīng)用,。
5,、2012.01-2014.12,教育部科學(xué)技術(shù)研究重點項目,,212202,,稻瘟病抗性基因Pi36互作蛋白的分子鑒定與功能研究。
6,、2010.01-2012.12,,湖北省自然科學(xué)杰出青年人才基金項目,,2009CDA125,稻瘟病廣譜抗性基因Pita-2的克隆及其應(yīng)用,。
7,、 2007.01-2009.12,國家自然科學(xué)青年基金項目,,30600400,,稻瘟病抗性基因Pi36的結(jié)構(gòu)及其功能研究。
8,、2007.01-2009.12,,武漢市青年科技晨光計劃,稻瘟病新抗性基因Pi39的定位及克隆” ,,200750731302,。
9、2005.10-2008.10,,中南民族大學(xué)自然科學(xué)基金重點項目,,YZZ05012,水稻紅蓮型細(xì)胞質(zhì)雄性不育相關(guān)基因HL-sp1的克隆及功能研究,。
(三)科研成果及榮譽
2015,,榮獲國家民委突出貢獻專家
2015,全國五一巾幗標(biāo)兵集體獎,,全國總工會,,排名第一
2014,湖北省高校教師黨支部書記“雙帶頭人”稱號,,湖北省高校工作委員會
2013,,高產(chǎn)優(yōu)質(zhì)抗稻瘟病雜交中稻品種駿優(yōu)522的選育與推廣,湖北省科技進步三等獎,,湖北省人民政府,,排名第五
2008,The in Silico map-based cloning of Pi36, a rice coiled-coil-nucleotide-binding site-leucine-rich repeat gene that confers race-specific resistance to the blast fungus,,湖北省第十二屆自然科學(xué)優(yōu)秀學(xué)術(shù)論文二等獎,,湖北省科技廳
(四)代表性論文
1. Yanping Tan, Shiqi Deng, Yonghua Qin, Xin Xu, You Yu, Liu Cui, Chuntai Wang, Changjie Jiang*, Xinqiong Liu*. Evaluation of Medicinal Plant Extracts for the Control of Rice Blast Disease. Rice Science, 2023, 30(1): 6-10.
2. Yanping Tan, Xiaolin Yang, Minghao Pei, Xin Xu, Chuntai Wang, Xinqiong Liu*. A Genome-wide Survey of Interaction between Rice and Magnaporthe oryzae via Microarray Analysis,Bioengineered,,2021, 12(1):108-116
3. Xinqiong Liu#, HaruhikoInoue#, Xianying Tang,Yanping Tan, Xin Xu, Chuntai Wang, Changjie Jiang*. Rice OsAAA-ATPase1 is induced during blast infection in a salicylic acid-dependent manner, and promotes blast fungus resistance. Int. J. Mol. Sci. 2020, 21(4):1443-1459
4. Yahong Chen, Kang Dai, Hua Zhang, Yunhua. Wu, Chuntai Wang, Xuequn Liu, Xinqiong Liu. Spectroscopic and molecular docking study on the interaction between salicylic acid and the induced disease-resistant protein OsAAA1 of rice. 2017, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 173, 1001–1006
5. Xinqiong Liu#, Haruhiko Inoue#, Nagao Hayashi, Chang-Jie Jiang, and Hiroshi Takatsuji . CC-NBS-LRR-TypeR Proteins for Rice Blast Commonly Interact with Specific WRKY Transcription Factors, Plant Mol Biol Rep, 2015, 34: 533-537. (IF2015=1.66)
6. Lixia Hua, L Q Liang, He X Y, Wang L, Zhang W S, Liu W, Xinqiong Liu, Fei Lin. Development of a marker specific for the rice blast resistance gene Pi39 in the Chinese cultivar Q15 and its use in genetic improvement. Biotechnology & Biotechnological Equipment, 2015, 29(3), 448-456
7. Debing Wang, Yonghua Qin, Jinluan Han, Zhang L, Xin Xu X, Xinqiong Liu , Chuntai Wang and Xinqiong Liu. Expression analysis of innate immunity related genes in the true/field blast resistance gene-mediated defence response. Biotechnology & Biotechnological Equipment, 2014, 28(6), 999-1007.
8. Han J L, Zhang X M, Zhang D, Liu X Q, Wang C T and Xinqiong Liu. Expression analysis of OsbZIP transcription factors in resistance response by the rice blast resistance gene Pi36-mediated. African Journal of Biotechnology, 2013, 12(34): 5294-5302
9. Jiang C J, Shimono M, Sugano S, Kojima M, Xinqiong Liu, Inoue H, Sakakibara H, Takatsuji H*. Cytokinins act synergistically with salicylic acid to activate defense gene expression in rice, Mol Plant Microbe Interact, 26(3):287-296, 2013
10. Inoue H, Hayashi N, Matsushita A, Xinqiong Liu, Nakayamab A, Sugano S, Jiang C J and Takatsuji H. Blast resistance of CC-NB-LRR protein Pb1 is mediated by WRKY45 through protein-protein interaction. Proc Natl Acad Sci USA, 2013, 110(23):9577–9582
11. He X Y#, Xinqiong Liu#, Wang L, Lin F, Cheng Y S, Chen Z M, Liao Y P, Pan Q H. Identification of the novel recessive gene pi55(t) conferring resistance to Magnaporthe oryzae. Sci China Life Sci, 2012, 55:141-9
12. Xinqiong Liu, Zhang D, Zhang X M, Wang C T, Liu X Q, Tan Y P, Wu Y H. Study on the interaction between Methyl asmonate and the coiled-coil domain of rice blast resistance protein Pi36 by spectroscopic methods. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2012, 88:72–76
13. Xinqiong Liu Wei J L, Zhang J C, Wang C T, Liu X Q, Zhang X M, Wang L, Pan Q H. Genetic variation of rice blast resistance genes in oryza sativa and its wild relatives. Int J Plant Sci, 2011, 172(8):970–979
14. Chen S#, Xinqiong Liu#, Zeng L X, Ouyang D M, Yang J Y, Zhu X Y. Genetic analysis and molecular mapping of a novel recessive gene xa34(t) for resistance against Xanthomonas oryzae pv. Oryzae. Theor Appl Genet, 2011, 122:1331–1338
15. Xinqiong Liu, Li Y, Wang L Y, Liu X, Wang C, Wang L, Pan Q H. The effect of the rice blast resistance gene Pi36 on the expression of disease resistance-related genes. Chinese Sci Bull, 2010, 55: 1881-1888
16. Xinqiong Liu, Wang L, Wang C, Liu X, Wang D, Lin F, Pan QH. The molecular evolution of the rice blast resistance gene Pi36. Int J Plant Sci, 2010, 171(3):235–243.
17. Xinqiong Liu, Yang Q Z, Wang L, Hua L X, Lin F and Pan Q H. Identification and fine mapping of Pi39(t), a major gene conferring the broad-spectrum resistance to Magnaporthe oryzae. Mol Genet Genomics, 2007, 278: 403–410
18. Xinqiong Liu, Lin F,,Wang L and Pan Q H. The in Silico map-based cloning of Pi36, a rice coiled-coil–nucleotide-binding site–leucine-rich repeat gene that confers race-specific resistance to the blast fungus,Genetics, 2007,,176: 2541–2549
19. Lin F, Chen S, Que Z, Wang L, Xinqiong Liu, Pan Q. The blast resistance gene Pi37 encodes a nucleotide binding site leucine-rich repeat protein and is a member of a resistance gene cluster on rice chromosome 1. Genetics, 2007, 177: 1871-80
20. Lin F, Liu Y G, Wang L, Xinqiong Liu, Pan Q H. A high-resolution map of the rice blast resistance gene Pi15 was constructed by sequence-ready markers. Plant Breeding, 2007, 126: 287-290
21. Xinqiong Liu, Wang L, Chen S, Lin F and Pan Q H. Genetic and physical mapping of Pi36(t), a novel rice blast resistance gene located on rice chromosome 8. Mol Genet Genomics, 2005, 274: 394-401
22.陳佳瑩,, 宋斯敏, 王春臺, 劉新瓊. 稻瘟病新抗性基因Pi39候選基因Pi39E長片段載體的構(gòu)建. 分子植物育種,,2019,,17( 9): 2882- 2885
23. 張旺, 陳佳瑩, 王春臺, 劉新瓊.水稻誘導(dǎo)抗病基因OsAAA1 啟動子構(gòu)建體的遺傳轉(zhuǎn)化與誘導(dǎo)表達(dá). 分子植物育種,2018,,16(21):7021-7026
24. 鄧霄霄, 劉早利, 王春臺, 劉新瓊, 水稻OsAAA1 基因啟動子的分離與克隆. 分子植物育種, 2017,15(8): 827-831
25. 劉早利, 陳亞紅, 王春臺, 劉新瓊. 稻瘟病新抗性基因Pi39候選基因CRISPR/Cas9敲除載體的構(gòu)建. 中國農(nóng)學(xué)通報, 2016, 32(6):91-95
26. 田迪, 劉早利, 陳亞紅, 王春臺, 劉新瓊. 水稻細(xì)胞色素P450基因家族成員CYP81A6基因RNAi載體構(gòu)建. 分子植物育種,,2016, 14(2): 370-373
27. 劉新瓊,,徐瑋玉,劉早利,,陳亞紅,,程鋼. 水稻OsAAA1蛋白的原核表達(dá)載體構(gòu)建及可溶性表達(dá)研究. 中南民族大學(xué)學(xué)報(自然科學(xué)版). 2015, 34(2):18-22
28. 袁坤, 張丹, 劉新瓊,張向明. 實時熒光定量PCR反應(yīng)體系的優(yōu)化研究. 廣東農(nóng)業(yè)科學(xué), 2013, 40(4):134-136
(五)發(fā)明專利
劉新瓊,,張佑宏,,楊小林,張向明,,王春臺,。一種七葉一枝花提取液的制備方法及其應(yīng)用,CN110663709B,,授權(quán)日期2021.6,,
劉新瓊,張佑宏,,楊小林,,張向明,王春臺,。一種蓮子心提取液的制備方法及其應(yīng)用,,CN110786341B,授權(quán)日期2021.4,,
劉新瓊,,徐鑫,譚艷平,,王春臺,,鄧霄霄。一種水稻誘導(dǎo)抗病基因OsAAA1啟動子及其載體與構(gòu)建方法,,ZL201710341677,,授權(quán)日期2019.11,
劉新瓊,,姜昌杰,,王春臺,程鋼,,劉學(xué)群. 一種水稻誘導(dǎo)抗病基因OsAAA1及其應(yīng)用,,ZL201410591365.6,,授權(quán)日期2016.8
潘慶華,王玲,,林菲,,劉新瓊. 稻瘟病抗性基因 Pi36及其應(yīng)用,ZL200610034048.X,,2009
(六)著作
王春臺,,劉新瓊,劉學(xué)群,,等. 圖解現(xiàn)代遺傳學(xué)實驗,,化學(xué)工業(yè)出版社,2009,,普通高等教育“十一五”規(guī)劃教材