
姓名:程崟家
職稱:副教授
單位:中南民族大學(xué)化學(xué)與材料科學(xué)學(xué)院
學(xué)科專業(yè):高分子化學(xué)和物理
研究方向:生物醫(yī)用高分子材料
學(xué)者簡(jiǎn)介:
程崟家(1988-),,女,,博士,,副教授,。2011年畢業(yè)于南華大學(xué),,獲得化工制藥專業(yè)學(xué)士學(xué)位,;2011-2016年在武漢大學(xué)化學(xué)與分子科學(xué)學(xué)院碩博連讀,,獲高分子化學(xué)與物理專業(yè)博士學(xué)位,。2016年8月起,,于中南民族大學(xué)化學(xué)與材料科學(xué)學(xué)院工作,。主要從事功能性納米材料的設(shè)計(jì)、構(gòu)建及其在生物醫(yī)學(xué)方面的應(yīng)用研究,。已在Biomaterials,、Journal of Controlled Release; ACS Applied Materials & Interfaces、Polymer Chemistry,、ACS Biomaterials Science & Engineering等國(guó)際SCI刊物上公開發(fā)表論文二十余篇,;申請(qǐng)國(guó)家發(fā)明專利4項(xiàng),授權(quán)3項(xiàng),;長(zhǎng)期擔(dān)任Adv. Sci., Adv. Funct. Mater., Acta Biomater., J. Mater. Chem. B, 等國(guó)際期刊的獨(dú)立審稿人,。
主持的科研項(xiàng)目
1. 國(guó)家自然科學(xué)基金面上項(xiàng)目(52472291),基于可降解介孔納米復(fù)合物構(gòu)筑智能型仿生納米平臺(tái)用于三陰性乳腺癌診療一體化研究,2025-2028,。
2. 國(guó)家自然科學(xué)基金面上項(xiàng)目(52173295),,“特洛伊木馬”型仿生納米復(fù)合材料的構(gòu)建及在腫瘤多模態(tài)精準(zhǔn)診療中的應(yīng)用,2022-2025,。
3.國(guó)家自然科學(xué)基金青年項(xiàng)目(51703251),,多功能富勒烯/介孔硅復(fù)合納米藥物控釋系統(tǒng)的構(gòu)建及其腫瘤診療的研究,2018-2020,。
已授權(quán)專利
1.程崟家,,秦四勇,張愛清,。一種聚集誘導(dǎo)發(fā)光多肽膠束型診斷試劑及其在近紅外區(qū)域生物成像中的應(yīng)用,,2022.0.17,中國(guó),,ZL202110709792.X,。
2.程崟家,,黎永秀,,秦四勇,張愛清,。一種酶敏感型多肽膠束型診斷試劑及其在制備抗腫瘤藥物中的應(yīng)用,,2022.05.30,中國(guó),,ZL202110540998.4,。
3.程崟家,余金鑫,,曾方宇,,劉強(qiáng)宇,張愛清,。一種紅細(xì)胞膜仿生修飾的“核-殼”型納米復(fù)合材料的制備方法及其應(yīng)用,,2024.08.09, 中國(guó), ZL 2024 1 0210240.8。
近年來發(fā)表的部分論文
1. Feng J.Q.#, Tian X.#, Cao R.G.#, Li Y.X., Liu W.L., Huang R.*, Qin S.Y.*, Zhang A.Q.*, Cheng Y.J. * An AIE-based theranostic nanoplatform for enhanced colorectal cancer therapy: Real-time tumor-tracking and chemical-enhanced photodynamic therapy. Chin. Chem. Lett., 2024, 35(12): 109657.
2. He Y., Chen Q.W., Yu J. X., Qin S. Y., Liu W. L., Ma Y. H., Chen X. S., Zhang A. Q., Zhang X. Z., Cheng Y. J.* Yeast cell membrane-camouflaged PLGA nanoparticle platform for enhanced cancer therapy. J Control Release, 2023, 359: 347-358.
3. Cheng Y. J.*, Qin S. Y., Liu W L, et al. Dual-Targeting Photosensitizer-Peptide Amphiphile Conjugate for Enzyme-Triggered Drug Delivery and Synergistic Chemo-Photodynamic Tumor Therapy. Adv. Mater. Interfaces, 2020, 7(19): 2000935. (Inside Cover)
4. Cheng Y. J. *, Hu J. J., Qin S. Y., et al. Recent advances in functional mesoporous silica-based nanoplatforms for combinational photo-chemotherapy of cancer. Biomaterials, 2020, 232, 119738.
5. Cheng Y. J. *, Qin S. Y., Ma Y. H., et al. Super-pH-Sensitive Mesoporous Silica Nanoparticle-Based Drug Delivery System for Effective Combination Cancer Therapy. ACS Biomaterials Science & Engineering, 2019, 5 (4), 1878-1886.
6. Cheng Y. J. *, Zhang A. Q., Hu J. J., et al. Multifunctional Peptide-Amphiphile End-Capped Mesoporous Silica Nanoparticles for Tumor Targeting Drug Delivery. ACS Applied Materials & Interfaces, 2017, 9, 2093-2103.
7. Cheng Y. J., Luo G. F., Zhu J. Y., et al. Enzyme-induced and tumor-targeted drug delivery system based on multifunctional mesoporous silica nanoparticles. ACS Applied Materials & Interfaces, 2015, 7, 9078-9087.
8. Cheng Y. J., Cheng H., Zhao X., et al. Self-assembled micelles of a multi-functional amphiphilic fusion (MFAF) peptide for targeted cancer therapy. Polymer Chemistry, 2015, 6, 3512-3520.
9. Xu X. D.#, Cheng Y. J. # (共同第一作者), Wu J., et al. Smart and hyper-fast responsive polyprodrug nanoplatform for targeted cancer therapy. Biomaterials, 2015, 76, 238-249.
10. Cheng Y. J., Zeng X., Cheng D. B., et al. Functional mesoporous silica nanoparticles (MSNs) for highly controllable drug release and synergistic therapy. Colloids and Surfaces B: Biointerfaces, 2016, 145, 217-225.
通訊地址:武漢市洪山區(qū)民族大道182號(hào)
E-mail:[email protected]